[Darya]
[Yu Long]
[Amir]
[Anh]
[Mais]
[Darya]
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2 место - продано (договор 612) 3 место - продано (договор 613) 4 место - продано (договор 614) 5 место - продано (договор 615) 6 место - продано (договор 616) 7 место - продано (договор 617) Дополнительно по статье: The article critically examines the practice of post-Chernobyl standardisation of radionuclide concentrations (mainly 137Cs and 90Sr) in food products (FPs) in the USSR and the successor countries of Belarus, Russia and Ukraine. Recommendations are given on potential harmonisation of these standards of radionuclide concentrations in FPs among the three countries, taking into account substantial international experience. We propose to reduce the number of product groups for standardisation purposes from the current amount of several dozens to three to five groups to optimise radiation control and increase the transparency of the process. We recommend five product groups for the standardisation of 137Cs and three groups for 90Sr in food in radiocontaminated areas. The values of standards for individual product groups are recommended to be set proportionally to the measured specific activity in each of these groups, which will reduce unreasonable food rejection. The standards might be set for the entire country, and could be also used to control imports from other countries as well as exports to other countries. The developed recommendations were transferred in 2015-2016 to the regulatory authorities of the three countries. Ключевые слова: Chernobyl accident; internal dose; public exposure; radionuclides in food; standardization Заказать публикацию № 61 Номер заказа № 61 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 622) 3 место - продано (договор 623) 4 место - продано (договор 624) 5 место - продано (договор 625) 6 место - продано (договор 626) Дополнительно по статье: Components of event-related potentials (ERP) were studied using an active sound signal discrimination task in northern schoolchildren aged 12?18 years with impaired mental development and learning difficulties (IQ 65 ? 4) and without mental developmental impairments (IQ 90 ? 10). The peak latency of the P300 component in the central and parietal areas of the cortex on perception and discrimination of target sound stimuli was greater in northern children with impaired mental development (Cz 370 ? 36 msec, 8.8 ? 4.1 V; Pz 375 ? 39 msec, 10.2 ? 3.3 V) as compared with their normally developing peers (339 ? 28 msec, 10.4 ? 3.0 V; 340 ? 35 msec, 12.2 ? 2.2 V, respectively). Negative correlations were found between cognitive abilities, the accuracy and speed of information processing in an attention task, and the latency of the P300 component, with positive correlations with the amplitude of the P3 component for measures of attention. The spatial, temporal, and amplitude characteristics of ERP in adolescents with impaired mental development reflect the functional incompetence or immaturity of the hierarchical organization of the system processing and discriminating information arriving in the brain and requiring concentration of attention and decision-taking. Ключевые слова: Arctic; attention; children; event-related potentials; intellect; P300 Заказать публикацию № 62 Номер заказа № 62 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 632) 3 место - продано (договор 633) 4 место - продано (договор 634) Дополнительно по статье: Objective: To analyze clinical and radiologic features of pathologic atlantoaxial displacement (PAAD) in pediatric patients and to compose a treatment algorithm for anomaly-related PAAD. Background: Criteria of different types of PAAD and treatment algorithms have been widely reported in the literature but are difficult to apply to patients with odontoid abnormalities, C2-C3 block, spina bifida C1, and children. Methods: We evaluated results of treatment of 29 pediatric patients with PAAD caused by congenital anomalies of the craniovertebral junction (CVJ), treated in Ilizarov Center in 2009?2017, including 20 patients with atlantoaxial displacement (AAD) and 9 patients with atlantoaxial rotatory fixation. Results: There were 14 males (48.3%) and 15 females (51.7%). We singled out 3 groups of patients: nonsyndromic (6 patients, 20.7%), Klippel-Feil syndrome (13 patients, 44.8%), and syndromic (10 patients, 34.5%). Odontoid abnormalities and C1 dysplasia were widely represented in the syndromic group. Local symptoms predominated in the nonsyndromic and KFS groups. In the syndromic group, all patients had AAD and myelopathy. A pronounced decrease of space available for chord C1 and increase of anterior atlantodental interval were noted compared with other groups. Conclusions: We present a unified treatment algorithm of pediatric anomaly-related PAAD. Syndromic AAD are often accompanied by anterior and central dislocation and myelopathy and atlantooccipital dissociation. These patients require early aggressive surgical treatment. Nonsyndromic and Klippel-Feil syndrome AAD, atlantoaxial subluxation, and atlantoaxial fixation often manifest by local symptoms and need to eliminate CVJ instability. Existing classifications of symptomatic atlantoaxial displacement are not always suitable for patients with CVJ abnormalities. Ключевые слова: Anomaly-related atlantoaxial dislocation; Congenital anomaly-related atlantoaxial subluxation; Congenital atlantoaxial dislocation Заказать публикацию № 63 Номер заказа № 63 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 642) 3 место - продано (договор 643) Дополнительно по статье: Background: Angiolipomas are mesenchymal tumors composed of mature adipocytes with abnormal vascular elements. They are most commonly found in subcutaneous tissues of the trunk and are rarely seen at craniospinal axes. Case Description: We present an untypical case of frontal lobe angiolipoma manifested with seizures and initially described as an arteriovenous malformation. Conclusion: MRI with fat-suppression sequence plays key role in angiolipomas diagnostics. Ключевые слова: AVM diagnosis; AVM treatment; Brain angiolipoma; Brain AVM; Supratentorial angiolipoma Заказать публикацию № 64 Номер заказа № 64 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 652) 3 место - продано (договор 653) 4 место - продано (договор 654) Дополнительно по статье: Dieulafoy disease can manifest itself with spontaneous massive recurrent gastrointestinal bleeding in children. We report a case of successful management of a 13-month-old child with Dieulafoy disease of duodenum when traditional methods of examination and treatment failed. Ключевые слова: Dieulafoy; Embolization; Gastrointestinal bleeding; Pediatrics Заказать публикацию № 65 Номер заказа № 65 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 662) 3 место - продано (договор 663) Дополнительно по статье: People judge food wasting as an immoral behavior. Although moral concerns vary widely across cultures, to this date, food wasting moral judgments were investigated only among rich and industrialized ones. This study reports first evidence of cultural variability on moral judgments of food wasting between modern and traditional cultures. We conducted our study among the Maasai - pastoralists of Ngorongoro, Yali - horticulturalists of West Papua, and among citizens of Poland. According to the results, Maasai judge food wasting as more immoral compared to Yali and Poles. Whats more, Yali judge food wasting harsher than Poles. These results suggest that there are cultural differences in moral judgments of food wasting. These differences might reflect the impact of unstable ecology on food economy of a given society. We hypothesize that harsh moral judgment concerning food waste may serve as a cultural adaptation for food insecurity. Заказать публикацию № 66 Номер заказа № 66 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 672) 3 место - продано (договор 673) 4 место - продано (договор 674) 5 место - продано (договор 675) Дополнительно по статье: Purpose: To estimate the effectiveness of complete corneal ring (MyoRing) implantation compared with MyoRing implantation combined with corneal collagen crosslinking (CXL) for keratoconus treatment for 36 months follow-up. Design: Retrospective cohort study. Materials and methods: MyoRing implantation was performed in a series of 78 patients (80 eyes) with keratoconus II?III Amsler classification, of these 39 eyes had MyoRing implantation combined with CXL. Implantation of a MyoRing in the corneal pocket was performed using a PocketMaker microkeratome and corneal intrastromal implantation system. During CXL, riboflavin solution 0.1% was injected into the corneal pocket through the incision tunnel and standard surface UVA irradiation (370 nm, 3 mW/cm2) was then applied from 5-cm distance for 30 min. Results: Significant improvements in uncorrected distance visual acuity and corrected distance visual acuity were observed for both groups, which was relatively better 12 months after procedure in MyoRing alone group; however, in 36 months there was no difference between groups. Keratometry was reduced in both groups; after MyoRing implantation for 8.45 D and MyoRing + CXL for 9.43 D, the spherical equivalent decreased from 8.45 to 7.72 D and from 9.43 to 6.25 D, respectively. The cylinder decreased to 3.33 D with MyoRing alone and to 3.31 D with MyoRing + CXL. Corneal thickness remained nearly unchanged (from 433.69 ? 38.76 to 434.21 ? 34.98) in MyoRing group and decreased from baseline (from 426.93 ? 46.58 to 401.24 ? 39.12 ?m) in MyoRing + CXL group 36 months postoperatively, which corresponds with pachymetry reduction after conventional CXL. Conclusion: Both MyoRing implantation and MyoRing combined with CXL were effective for treating keratoconus. At 36 months, there were slightly better outcomes in MyoRing + CXL group; however, in MyoRing alone group visual and refractive outcomes were stable overtime. Ключевые слова: Cornea; Corneal collagen crosslinking; Keratoconus; MyoRing Заказать публикацию № 67 Номер заказа № 67 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 682) 3 место - продано (договор 683) 4 место - продано (договор 684) 5 место - продано (договор 685) Дополнительно по статье: Background: This study investigated the non-genetic and genetic risk factors for arterial hypertension (AH) in two ethnic groups living in the Mountain Shoria region: Shors and non-indigenous people. Methods: Clinical and epidemiological study of compactly living population in the remote areas of the Mountain Shoria (Orton, Ust-Kabyrza, Sheregesh settlements, Kemerovo region). 1178 residents of these settlements were surveyed with the help of continuous sampling method; the sample consisted of adults (18 years and older). Results: The prevalence of AH was lower in Shors (39.9% vs. 46.1%), mainly due to differences between men from the different groups: 33.2% vs. 45.8%. The percentage of people with AH, overweight, and obesity (including transabdominal obesity) in the different age groups did not differ between ethnicities. We identified statistically significant differences in the prevalence of hypertension according the two ethic groups according to age, body weight, and abdominal obesity. I/D ACE and ADRA2B polymorphisms were associated with AH. In DD ACE and DD ADRA2B carriers, there were fewer hypertensive patients in Shors than in non-indigenous people: 40.6% vs. 58.6% and 38.3% vs. 64.0%, respectively. In DD ACE carriers, more Shors had AH (60.0% vs. 37.1%). Conclusion: Among Shors, the following factors increased AH risk: female sex, age, hypercholesterolemia, hyperbetacholesterinemia, hypertriglyceridemia, obesity (including transabdominal obesity), glucose intolerance, and the DD ACE, CT MTHFR, and AA ADRB1 genotypes; among the non-indigenous population, the main factors were age, hypercholesterolemia, hyperbetacholesterinemia, hypoalfacholesterinemia, hypertriglyceridemia, obesity (including transabdominal obesity), and ID ACE genotype. Ключевые слова: arterial hypertension; candidate genes; endothelial synthase gene; Ethnicity; I/D polymorphism Заказать публикацию № 68 Номер заказа № 68 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 692) 3 место - продано (договор 693) 4 место - продано (договор 694) 5 место - продано (договор 695) 6 место - продано (договор 696) 7 место - продано (договор 697) Дополнительно по статье: Achalasia is an extremely rare pathology in children. Peroral endoscopic myotomy (POEM) is the gold standard for the surgical treatment of achalasia in adults, but only a limited number of cases of achalasia treatment using POEM in children have been published in the literature. Sometimes, high-resolution manometry signs of achalasia can mimic diffuse esophageal leiomyoma. This case report represents the first known successful performance of POEM on a 15-year-old female with diffuse thickening of the esophagus with signs and symptoms of achalasia and suspicion for Alport syndrome associated with diffuse esophageal leiomyoma. Ключевые слова: Achalasia; Alport syndrome; Diffuse esophageal wall thickening; Esophagus; Peroral endoscopic myotomy Заказать публикацию № 69 Номер заказа № 69 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 702) 3 место - продано (договор 703) 4 место - продано (договор 704) 5 место - продано (договор 705) 6 место - продано (договор 706) Дополнительно по статье: Objectives. To study impulsivity in adolescents with attention deficit hyperactivity disorder (ADHD) and to evaluate the efficacy of Noofen (500 mg/day for 45 days) in the treatment of this pathology. Materials and methods. The results of clinical, psychological, and psychophysiological studies of 60 adolescents aged 12?15 years with ADHD are presented. The clinical pictures of illness and data from psychophysiological studies in ADHD with a predominance of hyperactivity (ADHD-H) and the combined type of illness (ADHD-C) were compared. Results and conclusions. Significantly higher levels of impulsivity and anxiety were found in children with ADHD-H. Treatment with Noofen was shown to have high clinical efficacy: status improved in 63.3% of patients. Ключевые слова: attention deficit hyperactivity disorder; impulsivity; Noofen Заказать публикацию № 70 Номер заказа № 70 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 712) 3 место - продано (договор 713) 4 место - продано (договор 714) 5 место - продано (договор 715) 6 место - продано (договор 716) 7 место - продано (договор 717) Дополнительно по статье: OBJECTIVES: Surgical interventional has been key in the treatment of tuberculosis (TB) for a long time. Its importance diminished after the emergence of chemotherapy. However, the spread of rapid multidrug-resistant (MDR) and extensively drug-resistant (XDR) TB has led us to return to surgery to treat TB. Today, every second patient in Russia with destructive TB has either MDR or XDR TB, which is the reason for the low efficacy of conservative treatment. In 2015, treatment with drugs resulted in clinical recovery in only 29.8% of new cases of destructive TB acid-fast bacilli (AFB)+. METHODS: The authors data from 1999 to 2016 have been analysed. The author performed 5599 surgeries on patients with pulmonary TB aged from 1 to 87 years (mean age 34.6 years). The most common reasons for surgical treatment were fibrotic cavitary and cavitary pulmonary TB, tuberculoma with destruction, tuberculous pleural empyema, caseous pneumonia and intrathoracic lymph nodes. The strategy of early collapse therapy and the use of surgery to treat TB was proposed in the Penza region of Russia; the results were analysed to estimate the long-term outcomes of treatment. RESULTS: In 5599 surgeries, the full clinical effect was achieved in 93% of operated patients with MDR TB, in 92.1% of those with XDR TB and in 98% of patients without MDR or XDR resistance. According to the data from the Penza region, 3 years after surgery, 93.9% (149 of 159 cases) of the operated patients exhibited clinical recovery. CONCLUSIONS: Taking into account the data from the World Health Organization on the insufficient level of therapeutic success in the treatment of MDR and XDR pulmonary TB, surgical treatment is necessary in regions with a high frequency of drug-resistant cases. Ключевые слова: Drug resistance; Pulmonary tuberculosis; Thoracic surgery Заказать публикацию № 71 Номер заказа № 71 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 722) 3 место - продано (договор 723) 4 место - продано (договор 724) 5 место - продано (договор 725) 6 место - продано (договор 726) Дополнительно по статье: Background: For intraventricular chemotherapy (IVC) as part of many oncological treatment protocols, Ommaya reservoir is enabling repeated access to the cerebro-spinal fluid (CSF). The correct placement of the catheter in the ventricle is essential for correct application of drugs, which is enabled by sophisticated techniques such as neuronavigation. Objective: In a bi-center retrospective study, we reviewed our experience using a smartphone-assisted ventricle catheter guide as simple solution for correct Ommaya reservoir placement. Methods: Sixty Ommaya reservoirs have been placed in 60 patients between 2011 and 2017 with the smartphone-assisted ventricular catheter guidance technique. Patient characteristics, preoperative frontal and occipital horn ratio (FOHR), postoperative catheter position, and complications were assessed. Results: The majority of our patients (71.6%) have got narrow or slit-like ventricles (FOHR 0.4). All Ommaya reservoirs were placed successfully. Fifty-eight ventricular catheters (97%) were inserted at the first and 2 (3%) at the second attempt using the same technique. No immediate perioperative complications were observed. All catheters (100%) could be used for IVC. Postoperative imaging was available in 52 patients. Thirty-two (61.5%) of ventricular catheters were rated as grade I, 20 (38.5%) as grade II, and none (0%) as grade III. Four patients (6.7%) showed postoperative complications during a median follow-up of 8.5 months (hydrocephalus, n = 1; infection, n = 1; parenchymal cyst around catheter, n = 1; shunt revision, n = 1). Conclusions: The smartphone-assisted guide offers decent accuracy of ventricle catheter placement with ease and simplicity for a small surgical intervention. We propose this technique as routine tool for Ommaya reservoir placement independent of lateral ventricular size to decrease the rate of ventricle catheter malposition as reasonable alternative to a neuronavigation system. Ключевые слова: Intrathecal chemotherapy (IVC); Neuronavigation; Ommaya reservoir; Stereotaxy; Thomale guide; Ventricular access device (VAD); Ventricular catheter Заказать публикацию № 72 Номер заказа № 72 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 732) 3 место - продано (договор 733) 4 место - продано (договор 734) Дополнительно по статье: To evaluate the association between the index and ring finger?s (2D:4D) length ratio with the prevalence and severity of radiographic hand osteoarthritis (OA). A population-based sample included 802 males (mean age 46.98 ? 17.10 years) and 738 females (mean age 48.65 ? 16.62 years) who had participated in a Chuvashian skeletal aging study. Age, sex, basic demographics, anthropometric data and X-rays of both hands were acquired. Each hand was visually classified on X-ray as either type 1?index finger longer than the ring finger; type 2?index and ring finger equal in length; or type 3?index finger shorter than the ring finger. Hand OA was defined by the number of affected joints (Kellgren?Lawrence score 2) in both hands and the sum total of Kellgren?Lawrence scores (total OA score). After comparing the OA variables of individuals with different finger length ratio types (after adjustment for age and BMI) significant differences were found only in females between finger ratio types of the right hand in a number of affected joints (F = 3.153, p = 0.043) and finger ratio types of the left (F = 3.330, p = 0.036) and right (F = 2.397, p = 0.047) hands of the total OA score. Females with type 3 ratios had the highest adjusted values of hand OA parameters. We found that finger length ratios are associated with hand OA parameters. Females with a type 3 finger length pattern showed significantly higher hand OA values than those with types 1 and 2. Ключевые слова: 2D:4D; Chuvash; Finger length ratio; Hand; Osteoarthritis Заказать публикацию № 73 Номер заказа № 73 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 742) 3 место - продано (договор 743) 4 место - продано (договор 744) Дополнительно по статье: Background: Oral health (OH) is poor among young adults in Russia, but there is little information on OH-related quality of life (OHRQoL) in this population. We investigated how socio-demographic factors, self-reported OH characteristics, oral health behaviour, and clinically-assessed OH are related to OHRQoL in medical and dental students in North-West Russia. Methods: This cross-sectional study included 391 medical and 275 dental Russian undergraduate students aged 18-25 years. Information on socio-demographic, self-reported OH characteristics, and oral health behaviour was obtained from a structured, self-administered questionnaire. A clinical examination was performed to assess dental caries experience based on the decayed (D) missing (M) filled (F) teeth (T) index; Simplified Oral Hygiene Index; and Gingival Index. OHRQoL was measured by the OH Impact Profile (OHIP-14). Results: 53.6% of students reported low OHRQoL during the last 12 months. Female sex (odds ratio [OR] = 1.48, 95% confidence interval [CI]: 1.00-2.19), rural place of childhood residence (OR = 1.56, 95% CI: 1.06-2.28), poor self-assessed dental aesthetic (OR = 1.75, 95% CI: 1.16-2.64), dissatisfaction with mouth and teeth (OR = 2.51, 95% CI: 1.68-3.77), and DMFT index (OR = 1.05, 95% CI: 1.01-1.09), were all significantly, independently associated with low OHRQoL. Conclusion: Socio-demographic factors (rural place of childhood residence, female sex), poor self-reported OH characteristics, and high DMFT index were associated with low OHRQoL. Ключевые слова: Medical and dental students; North-West Russia; Oral health-related quality of life Заказать публикацию № 74 Номер заказа № 74 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 752) 3 место - продано (договор 753) Дополнительно по статье: A ventricular septal aneurysm is a rare heart defect located in the muscular or membranous part of the septum. Muscular ventricular septal aneurysms are usually isolated, with a favorable prognosis. Membranous ventricular septal aneurysms are often associated with other heart anomalies, could result in serious complications, and may require surgical treatment. We describe 2 cases of prenatally diagnosed ventricular septal aneurysms: an isolated membranous ventricular septal aneurysm with a good outcome, which was initially misdiagnosed as an atrioventricular septal defect; and a muscular ventricular septal aneurysm associated with a hypoplastic aortic arch and severe hydrocephaly, which resulted in termination of the pregnancy. To our knowledge, the combination of a muscular ventricular septal aneurysm with an extracardiac anomaly has not been reported previously. Ключевые слова: differential diagnosis; echocardiography (fetal); extracardiac anomalies; ventricular septal aneurysm Заказать публикацию № 75 Номер заказа № 75 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 762) 3 место - продано (договор 763) 4 место - продано (договор 764) 5 место - продано (договор 765) 6 место - продано (договор 766) Дополнительно по статье: Background: Nowadays, there is no doubt that the development of infectious process is determined not only by individual features of a human, but also by features of infection agent. It is commonly known that ability to form an adequate immune response is based on immunogenetic peculiarities of macroorganism. Methods: The immunogenetic study was performed in 228 children from 1 to 15 years old with different manifestations of tuberculosis (TB). Control group was consisted of 446 adult healthy donors-residents of the Northwestern region of Russia. Human leukocyte antigens (HLA)-DRB1 allelic genes were assessed in all individuals. Results: HLA-DRB1 alleles 01, 03, 11, 13, 07, and 15 were observed significantly rare in children with TB in comparison with healthy donors that may indicate their protective role in the development of the disease. It was also noticed that DRB1 07 and 15 alleles were observed significantly rare in children with lung TB in comparison with other forms of disease that allows to assume a protective function of these alleles for lung TB with no influence on development of generalized TB. This assumption requires further researches. Conclusion: As a result of the study, statistically significant differences in the distribution of HLA-DRB1 alleles in children with TB in comparison with a control group for 01, 03, 11, 13, 07, 15, and 16 alleles were found. It may indicate their protective role in the development of TB. DRB1 07 and 15 alleles were observed significantly rare in children with single TB than in children with generalized TB and healthy controls. Ключевые слова: Children; genotyping; HLA alleles; immunogenetic diagnosis; tuberculosis Заказать публикацию № 76 Номер заказа № 76 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 772) 3 место - продано (договор 773) 4 место - продано (договор 774) 5 место - продано (договор 775) 6 место - продано (договор 776) Дополнительно по статье: Objectives: To determine antibiotic susceptibility in isolates of Streptococcus pneumoniae and Haemophilus influenzae collected in 2014-16 from Russia. Methods: MICs were determined by CLSI broth microdilution and susceptibility was assessed using CLSI, EUCAST and pharmacokinetic/pharmacodynamic (PK/PD) breakpoints. Results: A total of 279 S. pneumoniae and 279 H. influenzae were collected. Overall, 67.0% of S. pneumoniae were penicillin susceptible by CLSI oral/EUCAST and 93.2% by CLSI intravenous (iv) breakpoints. All were fluoroquinolone susceptible, with amoxicillin, amoxicillin/clavulanic acid and ceftriaxone susceptibility 92.8%by CLSI and PK/PD breakpoints. Isolates showed lower susceptibility to cefuroxime, cefaclor, macrolides and trimethoprim/ sulfamethoxazole by CLSI criteria: 85.0%, 76.7%, 68.8% and 67.7%, respectively. Generally, susceptibility was slightly lower by EUCAST criteria, except for cefaclor, for which the difference in susceptibility was much greater. Penicillin-resistant isolates had low susceptibility (60%) to all agents except fluoroquinolones. All 279 H. influenzae were ceftriaxone susceptible, 15.4% were b-lactamase positive and 97.5% were amoxicillin/ clavulanic acid susceptible (CLSI, EUCAST and PK/PD breakpoints). Four isolates were fluoroquinolone nonsusceptible by current EUCAST criteria. A major discrepancy was found with azithromycin susceptibility between CLSI (99.3%) and EUCAST and PK/PD (2.2%) breakpoints. Trimethoprim/sulfamethoxazole was poorly active (62.7% susceptible). Conclusions: Susceptibility to penicillin (oral), macrolides and trimethoprim/sulfamethoxazole was low in S. pneumoniae from Russia. However, isolates were fully susceptible to fluoroquinolones and 92.8% were susceptible to amoxicillin, amoxicillin/clavulanic acid and ceftriaxone. Isolates of H. influenzae only showed reduced susceptibility to ampicillin, cefaclor, clarithromycin and trimethoprim/sulfamethoxazole. Some differences were detected between CLSI, EUCAST and PK/PD breakpoints, especially with cefaclor, cefuroxime and macrolides. These data suggest further efforts are required to harmonize international breakpoints. Заказать публикацию № 77 Номер заказа № 77 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 782) 3 место - продано (договор 783) 4 место - продано (договор 784) Дополнительно по статье: Objective: This multiple-case study explores the self-protective attachment strategies of adults with ADHD and the history of the dangers in their family of origin. Method: Nine respondents were interviewed using the Adult Attachment Interview, AAI (The Dynamic Maturational Model modification). Results: All respondents had experienced dangers connected to the lack of protection and comfort in their families of origin, including unresolved traumas, such as early emotional neglect, later supervision neglect, abuse and witnessing discord, even domestic violence, in triangulated family relationships. Three subgroups were formed on the basis of the attachment classifications. Conclusions: The recognition of the variety of attachment strategies, disorientation modifying, and unresolved traumas interrupting the strategic self-protective functioning, can contribute to the tailoring of individualized psychological treatment. The psychological treatment would help these adults with ADHD to understand how the unresolved traumas and triangulated family systems have impacted and still impact them. Ключевые слова: Abuse; ADHD; Adult attachment interview; Attachment strategies; Domestic violence; Emotional neglect; Later supervision neglect; Strategic self-protective functioning; Unresolved traumas; Witnessing discord Заказать публикацию № 78 Номер заказа № 78 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 792) 3 место - продано (договор 793) 4 место - продано (договор 794) Дополнительно по статье: Chronic rhinosinusitis (CRS) is an inflammatory disease of the nose and paranasal sinuses affecting 11% of the European population. Cyclamen europaeum plant extract (CE) has demonstrated efficacy in treating acute rhinosinusitis, but its role in CRS exacerbations remains unknown. In this real-life, prospective, epidemiological, observational study, a total of 317 patients with exacerbations of CRS without nasal polyps (CRSsNP) of moderate severity were treated using three different options: oral antibiotics, CE extract nasal spray, or the combination of oral antibiotic with CE extract. The main outcomes were the effect of treatment on sinonasal symptoms and endoscopic appearance after 6 weeks of therapy, and the number of recurrences of CRS exacerbations after 6 months of follow-up. On the top of oral antibiotics, CE extract significantly improved sinonasal symptoms and endoscopic findings and caused a 4-fold reduction of CRS recurrences. When administered in monotherapy, CE extract was at least as effective as antibiotic in monotherapy on relief of both symptoms and reduction of CRS recurrences. In patients with CRS exacerbation of moderate severity, CE extract nasal spray in monotherapy or added to standard antibiotic treatment significantly reduces sinonasal symptoms and CRS recurrences compared to antibiotics in monotherapy. Ключевые слова: Antibiotics; Chronic rhinosinusitis; Cyclamen europaeum; Nasal endoscopic score; Observational study; Real life; Symptom score Заказать публикацию № 79 Номер заказа № 79 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 802) 3 место - продано (договор 803) 4 место - продано (договор 804) 5 место - продано (договор 805) Дополнительно по статье: Examination of the residents of two areas in the Penza region has shown that, compared to the regional center, they show higher case rate of inflammatory periodontal diseases. Such diseases often cause loss of teeth, including among young people. This in turn leads to morphological and functional changes in the masticatory apparatus, which adversely affects the digestive organs, thus impairing facial aesthetics, chewing and speech. In order to adequately assess the case rate, epidemiological dental surveys of the population are performed according to the uniform criteria recommended by the WHO. Such surveys allow to unbiasedly assess the level of oral health among the population, plan preventive programs, and predict future needs of the population in dental care. Ключевые слова: Dental morbidity rate; Intensity; Periodontium; Prevalence; Treatment Заказать публикацию № 80 Номер заказа № 80 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 812) 3 место - продано (договор 813) 4 место - продано (договор 814) Дополнительно по статье: Background: Elevated levels of C-reactive protein (CRP), a sensitive marker of inflammation, have been consistently reported in chronic spontaneous urticaria (CSU). Here, we retrospectively analyzed data from 1253 CSU patients from 2 centers to answer the following questions: (i) What is the prevalence of elevated levels of CRP in CSU? (ii) Why do CSU patients show elevated levels of CRP? (iii) Are elevated CRP levels relevant?. Methods: Serum levels of CRP were measured by the nephelometric method. We collected information regarding various laboratory tests including ESR, CBC with differential, D-dimer, fibrinogen, C3, C4, IL-6, etc. For most patients, we also collected data on age, gender, duration of CSU, presence of angioedema, activity (UAS at the time of blood sampling and for 7 days), quality of life (CU-Q2oL and/or DLQI), comorbidities and possible causes of CSU, and autologous serum skin test (ASST) response. The efficacy of second-generation antihistamines was evaluated on the day of blood collecting. Results: One-third of CSU patients had elevated levels of CRP. Higher levels of CRP were associated with ASST positivity (P =.009) and arterial hypertension (P =.005), but not with other possible causes or comorbidities of CSU. C-reactive protein correlated with urticaria activity (P .001), quality of life impairment (P =.026), and inflammatory and coagulation markers (P .001). C-reactive protein levels were significantly higher in nonresponders to antihistamines as compared to responders (P .001). Conclusion: Elevated levels of CRP are common and relevant in CSU patients. The assessment of CRP levels may help to optimize the management of patients with CSU. Ключевые слова: antihistamines; C-reactive protein; chronic spontaneous urticaria; disease activity; marker Заказать публикацию № 81 Номер заказа № 81 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 822) 3 место - продано (договор 823) 4 место - продано (договор 824) 5 место - продано (договор 825) 6 место - продано (договор 826) 7 место - продано (договор 827) Дополнительно по статье: Methylphenidate (MPH) has been shown to modulate the amplitude of the no-go P3 component of the event-related potential (ERP; grim, Aasen, & Brunner, 2016). Using group independent component analysis, the no-go P3 from a cued go/no-go task has been separated into two sub-components (Brunner et al., 2013). This study investigated whether sub-components of the no-go P3 could be identified in children with ADHD, and how MPH modulates their amplitudes. ERPs were registered twice (on/off MPH) in 57 children with ADHD classified as medication responders in a four-week medication trial. Two no-go P3 sub-components were identified. In the MPH session, the amplitude of one sub-component, the IC P3no-goearly (mean latency 378 ms, with a central distribution), was significantly larger than at baseline, whereas the other sub-component, the IC P3no-golate (mean latency 428 ms, with a centro-frontal distribution), was not significantly affected. These results add to the literature documenting that the no-go P3 consists of two overlapping phenomena with different functional correlates. Ключевые слова: ADHD; Cued go/no-go; ICA; MPH; No-go P3 Заказать публикацию № 82 Номер заказа № 82 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 832) 3 место - продано (договор 833) 4 место - продано (договор 834) 5 место - продано (договор 835) 6 место - продано (договор 836) 7 место - продано (договор 837) Дополнительно по статье: Attention deficit hyperactivity disorder (ADHD) is a neuropsychiatric disorder characterized by a developmentally inappropriate, pervasive and persistent pattern of severe inattention, hyperactivity and impulsivity. Despite onset in early childhood, ADHD may continue into adulthood with substantial impairment in social, academic and occupational functioning. A new animal model of this disorder was developed in rats with genetic deletion of the dopamine transporter (DAT) gene (dopamine transporter knockout rats; DAT-KO rats). We analyzed the behavior of DAT-KO rats for a deeper phenotypical characterization of this model. We first tested rats of the 3 genotypes at different ages (preadolescent, adolescent and adult), in a novelty-seeking test using a black/white box (Experiment 1). After that, we tested adult rats in a novelty-preference test using a 3-chamber apparatus with different shapes (Experiment 2). Experiment 1: as evidenced by analysis of time spent in the novel environment, adult DAT heterozygous (DAT-HET) rats show an increased curiosity-driven exploration compared with wild-type (WT) controls while DAT-KO rats did not recognize novelty. The locomotor activity data show a minimal difference between genotypes at adolescent age while the preadolescent and adult DAT-KO rats have significantly increased activity rate compared with WT and DAT-HET subjects. Experiment 2: in this case, due to more clearly evident spatial differences, time spent in novel environment was not significantly different among genotypes. During first 10 minutes, DAT-KO rats showed a decreased hyperactivity, apparently related to curiosity and attention to the new environments. In conclusion, DAT-KO rats may show some inattention while more novelty-seeking traits appear in DAT-HET rats. Ключевые слова: ADHD; adolescence; DAT-HET (heterozygous); explorative curiosity; hippocampus; inattention; juvenile; novelty preference; novelty seeking; prefrontal cortex Заказать публикацию № 83 Номер заказа № 83 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 842) 3 место - продано (договор 843) 4 место - продано (договор 844) 5 место - продано (договор 845) Дополнительно по статье: Objective: To evaluate the optimal timing and type of surgical treatment of myelomeningocele (MMC)-related spinal deformities and long-term follow-up of surgical treatment. Methods: We reviewed and presented clinical pictures, treatment strategies and results of 20 patients with MMC-related spinal deformities treated at our center between 2010 and 2017. Results: The average patient age was 6.3 years. The average preoperative neurologic status according to a modified Japan Orthopedic Association (mJOA) scale was 7.3 points (Benzels modification). Average functional status was 41 points according to a functional independent measure scale (FIM). The average angle of kyphosis was 83.7? that of scoliosis was 36.7? and that of lordosis was 67? (Cobb angles). The average duration of surgery was 234 minutes, and the average total blood loss was 175 mL. The average angle of kyphosis correction was 61? that of scoliosis correction was 25? and that of lordosis correction was 25? (Cobb angles). The average duration of hospitalization was 16.6 days, and the average follow-up was 34.5 months. The total number of complications was 13. Reoperation was required in 9 cases. Neurologic status according to the mJOA scale improved by 0.6 point on average. Functional status according to the FIM increased by 6.6 points on average. Conclusions: Early surgical correction of MMC-related spinal deformities improves body balance and quality of life. The dual growing rod technique is safe and effective in cases of moderate neuromuscular spinal deformities at an early age. Kyphectomy is a challenging procedure with high complication rates, especially skin problems, but there are no alternative procedures for cases of heavy rigid kyphosis. Ключевые слова: Myelomeningocele-related spinal deformity; Post-myelomeningocele syndrome; Sharp-angled kyphosis Заказать публикацию № 84 Номер заказа № 84 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 852) 3 место - продано (договор 853) 4 место - продано (договор 854) 5 место - продано (договор 855) 6 место - продано (договор 856) Дополнительно по статье: This study cross-culturally investigated resilience and social support as possible protective factors for mental health. The values of depression, anxiety, and stress symptoms, resilience and social support were collected from German (N = 4433), Russian (N = 3774), and Chinese students (N = 4982). The samples were split (two-thirds vs. one-third) to cross-validate the results. In all samples, resilience and social support were significantly negatively associated with depression, anxiety, and stress symptoms. While in Germany those associations were stronger for social support, in Russia and in China stronger associations were found for resilience. Furthermore, in all samples, resilience was found to mediate the association between social support and the negative mental health variables significantly. In conclusion, resilience and social support are universal interrelated protective factors for mental health independently of historical, cultural, social, and geographical conditions of a country. Ключевые слова: China; Germany; negative mental health; Resilience; Russia; social support Заказать публикацию № 85 Номер заказа № 85 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 862) 3 место - продано (договор 863) 4 место - продано (договор 864) 5 место - продано (договор 865) Дополнительно по статье: Children use numbers every day and typically receive formal mathematical training from an early age, as it is a main subject in school curricula. Despite an increase in children neuroimaging studies, a comprehensive neuropsychological model of mathematical functions in children is lacking. Using quantitative meta-analyses of functional magnetic resonance imaging (fMRI) studies, we identify concordant brain areas across articles that adhere to a set of selection criteria (e.g., whole-brain analysis, coordinate reports) and report brain activity to tasks that involve processing symbolic and non-symbolic numbers with and without formal mathematical operations, which we called respectively number tasks and calculation tasks. We present data on children 14 years and younger, who solved these tasks. Results show activity in parietal (e.g., inferior parietal lobule and precuneus) and frontal (e.g., superior and medial frontal gyri) cortices, core areas related to mental-arithmetic, as well as brain regions such as the insula and claustrum, which are not typically discussed as part of mathematical problem solving models. We propose a topographical atlas of mathematical processes in children, discuss findings within a developmental constructivist theoretical model, and suggest practical methodological considerations for future studies. Ключевые слова: Children; Development; fMRI; Insula; Mathematical cognition; Meta-analyses Заказать публикацию № 86 Номер заказа № 86 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 872) 3 место - продано (договор 873) 4 место - продано (договор 874) Дополнительно по статье: The sexually transmitted infections represent an actual medical social problem. The purpose of study is to analyze characteristics of their prevalence in various social groups of population. The data from annual reports on morbidity in the Republic of Udmurtia in 2006-2015 is analyzed. The analysis of morbidity of sexually transmitted infections during the mentioned period demonstrated the highest morbidity of chlamydia infection (from 135 in 2006 to 194,8 in 2015 per 100 000 of population) and trichomoniasis (from 63.5 in 2006 to 183.4 in 2015 per 100 000 of population). In the structure of morbidity in 2006 trichomoniasis went to 25.6?1.2%, chlamydia infection -- 19?0.9%, syphilis -- 17.6?0.8%. In the end of analyzed period, chlamydia infection was in the lead in overall structure of morbidity. The analysis of morbidity subject to social belonging demonstrated that in relation to syphilis and trichomoniasis preponderance the diseased was in the direction of non-working population while in case of other infections in the direction of workers of middle and minor business. The results of study demonstrated the necessity of development of activities in area of primary prevention among working population, workers of middle and minor business and student youth. Ключевые слова: middle and minor business; morbidity; non-working population; sexually transmitted infections; social belonging Заказать публикацию № 87 Номер заказа № 87 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 882) 3 место - продано (договор 883) Дополнительно по статье: The article presents the results of analysis of trends in morbidity and dispensary observation of Moscow adult population with diseases of musculoskeletal system and connective tissue. The analysis was applied to data from statistical report forms # 12 of the Moscow Health Care Department in 2012-2016. The stability of percentage of diseases of musculoskeletal system in the structure of total and primary morbidity during last 5 years was established. The significant dynamics of indices of total morbidity is absent. The statistically significant descending trend if primary morbidity at the expense of deforming dorsopathies in the age group older than 55 years was established. The deforming dorsopathies hold first place in the structure of diseases of musculoskeletal system. The dynamics of decreasing of indices of total morbidity of the given pathology in the age group of 18-55 years and older than 55 years is statistically non-significant. The statistically significant ascending tendency of indices of total morbidity of arthroses of adult population and primary morbidity of synovial membranes and tendons in the age group of 18-55 years is established. The established in adult population and individuals aged 18-55 years both decreasing of number of being dispensary registered on the subject of pathology of musculoskeletal system and its increasing among individuals older than 55 years are statistically non-significant. The trend of dropping of indicator of being on dispensary registration of individuals with primarily diagnosed pathology is also insignificant. The correlation between rate of dispensary registration and primary morbidity, including particular pathologies, is absent. Ключевые слова: diseases of musculoskeletal system; dispensary observation; morbidity Заказать публикацию № 88 Номер заказа № 88 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 892) 3 место - продано (договор 893) 4 место - продано (договор 894) 5 место - продано (договор 895) Дополнительно по статье: BACKGROUND: To determine the features of heart rate variability in hockey players aged from 13 to 16. METHODS: A total of 97 hockey players aged 13 to 16 years who were studying at the specialized childrens and youth school of the Olympic reserve of the Ural region of Russia were examined. The ECG was recorded at rest and during an active orthostatic test. Standard methods of time analysis, frequency analysis of heart rate variability (HRV) and variational pulseometry were used in the work. The reactivity of the parasympathetic autonomic nervous system was determined by a factor of 30:15 in the transition period of the active orthostatic test. RESULTS: The most significant changes in the parameters of HRV in hockey groups occur at 16 years: a lower CV value relative to hockey players of 14 years (P0.001), a larger value of RMSSD relative to hockey players of 13 years (P0.05) and a lower value of VLR relative to all younger age Groups of players (P0.05, P0.05 and P0.01, respectively). The total power of regulation (TR) in all age groups of hockey players was the same. At 16 years, hockey players have more HF and HF%, while less VLF% relative to hockey players 13 years; Less VLF and VLF% relative to hockey players 14 years. The value of the coefficient of 30:15 hockey players is 14 years, 15 years and 16 years more relative to hockey players of 13 years (P0.01, P0.001 and P0.001, respectively). The ratio of hockey players of 13-16 years with I, II, III and IV types of regulation differed depending on age. At 13 years the ratio was: 36%: 7%: 50%: 7%; In 14 years: 25%: 0%: 46%: 29%; In 15 years: 36%: 0%: 46%: 18%; In 16 years: 15%: 2%: 73%: 10%. CONCLUSIONS: By the age of 16, hockey players have an increase in the overall effect of heart rate regulation by increasing the influence of the parasympathetic nervous system and reducing the effect of cerebral-ergotropic regulation mechanisms, which is accompanied by a decrease in the heart rate. By the age of 15, the reactivity of the parasympathetic nervous system of hockey players in an active orthostatic test increases. In groups of hockey players of adolescence, the distribution by type of regulation differs depending on age. The number of types with the predominance of autonomous regulatory mechanisms increases at the age periods from 13 to 14 years and from 15 to 16 years. The relative number of hockey players with the IV type of heart rate regulation decreases from 14 years to 16 years. The greatest tension in the mechanisms for the heart rate regulation of hockey players is observed in 13 years and 15 years. Ключевые слова: Adolescent; Athletes; Heart rate; Hockey Заказать публикацию № 89 Номер заказа № 89 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |
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2 место - продано (договор 902) 3 место - продано (договор 903) 4 место - продано (договор 904) 5 место - продано (договор 905) 6 место - продано (договор 906) Дополнительно по статье: BACKGROUND: Determine the characteristics of the dynamics of physical development of children and adolescent hockey players, depending on the player position. METHODS: A total of 189 male children and adolescents were examined, 156 of them were hockey players (95 attackers and 65 defenders), which formed the age groups: 7-8 years, 9-10 years, 11-12 years, 13 years, 14 years, 15 years and 16 years. All hockey players were engaged in a specialized childrens and youth school of the Olympic reserve for hockey. Standard anthropometric methods for studying length and body weight, as well as calculation of Body Mass Index (BMI) were used in the work. RESULTS: In the age aspect, three periods of a significant increase in the anthropometric indicators of hockey players are determined: for body weight IT is 11-12 years, 14 and 16 years, for body length it is 11-12 years, 14 and 15 years. In the period from 15 to 16 years there is a significant increase in BMI due to the excess of the growth rates of body weight of hockey players over the body length. The maximum increase in all indicators simultaneously - body length, body weight and BMl - occurs from 9-10 to 11-12 years regardless of the players position. Further, the greatest increase in the total body size and BMI of the body length of the hockey players, depending on the player position, corresponds to different periods: for attackers at 14 years (body length), at 16 years (body weight and BMI), for defenders at 13 years (length body and body weight), at 14 years (BMI). CONCLUSIONS: Changes in the parameters of physical development of children and adolescent hockey players-defend-ers as compared to hockey-attackers are characterized by smaller amplitude of fluctuations in values. The periods of 13 and 15 years are critical periods in the physical development of attackers judging by the growth of BMI. Ключевые слова: Adolescent; Body Mass Index; Body weights and measures; Growth and development; Hockey Заказать публикацию № 90 Номер заказа № 90 Самый быстрый и простой способ заказать или задать вопрос, написать нам: Все контакты |